Hypoxia-inducible factor-1α as a predictive marker in pre-eclampsia
نویسندگان
چکیده
منابع مشابه
Hypoxia, Hypoxia-Inducible Factor-1α, and Innate Antileishmanial Immune Responses
Low oxygen environments and accumulation of hypoxia-inducible factors (HIFs) are features of infected and inflamed tissues. Here, we summarize our current knowledge on oxygen levels found in Leishmania-infected tissues and discuss which mechanisms potentially contribute to local tissue oxygenation in leishmanial lesions. Moreover, we review the role of hypoxia and HIF-1 on innate antileishmania...
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Liver fibrosis is characterized by excessive deposition of extracellular matrix in the liver during chronic injury. During early stages of this disease, cells begin to synthesize and secrete profibrotic proteins that stimulate matrix production and inhibit matrix degradation. Although it is clear that these proteins are important for development of fibrosis, what remains unknown is the mechanis...
متن کاملExpression of hypoxia-inducible factor 1α in thyroid carcinomas
Hypoxia-inducible factor 1 alpha (HIF-1 alpha) is upregulated by hypoxia and oncogenic signalling in many solid tumours. Its regulation and function in thyroid carcinomas are unknown. We evaluated the regulation of HIF-1 alpha and target gene expression in primary thyroid carcinomas and thyroid carcinoma cell lines (BcPAP, WRO, FTC-133 and 8505c). HIF-1 alpha was not detectable in normal tissue...
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ژورنال
عنوان ژورنال: Biomedical Reports
سال: 2012
ISSN: 2049-9434,2049-9442
DOI: 10.3892/br.2012.44